Annonaceous acetogenins are highly bioactive compounds produced by cherimoya, soursop, custard apple, and other members of the annonacea family.

Despite ingestion toxicity, studies indicate that acetogenins exhibit anti-inflammatory, anti-tumorigenic, antineoplastic, and antimicrobial effects, showing promise as a potential anticancer agent.

Annonacae leaves, bark, seeds, and roots contain toxic acetogenin concentrations. The fruit pulp contains tolerable amounts appropriate for direct consumption by the frugivorous man.